Solute-Matrix and Solute-Solute Interactions During Supercritical Fluid Extraction of Sea Buckthorn Leaves

Analysis of Free Solute Fractions and Solute-Protein Interactions Using Ultrafast Affinity Extraction and Affinity Microcolumns

Dipolar solute rotation in a supercritical polar fluid.

Fluorescence anisotropy measurements reveal a non-monotonic density dependence for average rotation time (τ(R)) of a polar solute, coumarin153 (C153) in polar supercritical fluoroform (CHF(3)). The conventional Stokes-Einstein-Debye model, relating τ(R) to the solvent viscosity, fails to explain the observed density dependence, because the experimental viscosity increases monotonously with dens...

Concentration Polarization Phenomena during Dead-end Ultrafiltration of Protein Mixtures. the Influence of Solute-solute Interactions

The flux decline behaviour of some charged proteins and of binary mixtures of charged solutes during unstirred dead-end ultrafiltration has been studied. The mixtures consisted of the proteins bovine serum albumin, (BSA), cy-lactalbumin and/or lysozyme. Of special interest were a-lactalbumin and lysozyme because these proteins are physico-chemically identical, except for the sign of their charg...

Solvation of diclofenac in water from atomistic molecular dynamics simulations - interplay between solute-solute and solute-solvent interactions.

The solubility-permeability relationship of active pharmaceutical ingredients determines the efficacy of their usage. Diclofenac (DCL), which is a widely used nonsteroidal anti-inflammatory drug, is characterized by extremely good membrane permeability, but low water solubility limiting drug effectiveness. The present research focuses on the fundamental explanation of this limitation using the ...

Extraction of model parameters for reactive solute transport

In the present study, tried to examine the reactive solute relationships for transport and degradation processes through the rockfill media. By applying the analytical solution of reactive transport, the 1st to 3rd theoretical temporal moments have been extracted then, by using two methods of curve fitting and temporal moment matching, the coefficients of dispersion and degradation have been ex...